BDBM50182554 CHEMBL3818731::US9512121, 8

SMILES [H][C@]12CCCN1c1cnc3ccc(Sc4nnc5c(F)cc(cn45)-c4cnn(C)c4)cc3c1OC2

InChI Key InChIKey=AVLLGHFOBOLCPF-MRXNPFEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182554   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50182554(CHEMBL3818731 | US9512121, 8)
Affinity DataIC50:  37nMAssay Description:Inhibition of c-Met (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50182554(CHEMBL3818731 | US9512121, 8)
Affinity DataIC50:  37nMT: 2°CAssay Description:Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...More data for this Ligand-Target Pair
In DepthDetails US Patent