BDBM50182563 1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one::CHEMBL379446

SMILES CCCC(N1CCCC1)C(=O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=NAHZCGQMXZCULW-UHFFFAOYSA-N

Data  3 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50182563   

TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataKi:  266nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 531nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of [3H] serotonin uptake into human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataKi:  2.46E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataKi:  2.69E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against dopamine D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against dopamine D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against 5HT1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against 5HT1CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against dopamine D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182563(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed