BDBM50182565 4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)pentan-1-one::CHEMBL202409

SMILES CC(C)CC(N1CCCC1)C(=O)c1ccc(C)cc1

InChI Key InChIKey=GMWFVXBLHOYMAG-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50182565   

TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182565(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182565(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)
Affinity DataKi:  13.7nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182565(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182565(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)
Affinity DataKi:  259nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182565(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of [3H] serotonin uptake into human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182565(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)
Affinity DataKi:  2.87E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed