BDBM50182584 2pyrrolidin-1-yl-1-phenylpentan-1-one::CHEMBL205082

SMILES CCCC(N1CCCC1)C(=O)c1ccccc1

InChI Key InChIKey=YDIIDRWHPFMLGR-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50182584   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50182584(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)
Affinity DataKi:  33.7nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50182584(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)
Affinity DataKi:  199nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50182584(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50182584(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)
Affinity DataIC50:  56nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50182584(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)
Affinity DataIC50:  52.3nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed