BDBM50182692 CHEMBL202424::N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-2-heptynamide

SMILES: CCCCC#CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cn1

InChI Key: InChIKey=PEOYVSCYYMEJBB-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50182692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50182692 (N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM50182692 (N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50182692 (N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50182692 (N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50182692 (N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair