BDBM50182720 CHEMBL3819344

SMILES CCCN1CCN(Cc2ccc(cc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(CC(C)C)CC(=O)NC(Cc2ccsc2)C(N)=O)[C@@H](C)C1

InChI Key InChIKey=ASFDWCMXZHPPAH-JGKWCCMASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182720   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50182720(CHEMBL3819344)
Affinity DataIC50:  2.24E+4nMAssay Description:Inhibition of recombinant human CDK2/cyclin A2 using fluoresceinyl-Ahx-Pro-Val-Lys-Arg-Arg-Leu-Phe-Gly as substrate incubated for 45 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50182720(CHEMBL3819344)
Affinity DataIC50:  9.36E+3nMAssay Description:Inhibition of recombinant human CDK4/cyclin D1 using fluoresceinyl-AhxPro-Val-Lys-Arg-Arg-Leu-(3ClPhe)-Gly as substrate incubated for 45 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed