BDBM50182801 (3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8::(3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol::5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE::AFEGOSTAT TARTRATE::CHEMBL206468::D-Isofagomine::US10081601, Example 1.1::US9796680, Example Table2.1::isofagomine

SMILES: OC[C@H]1CNC[C@@H](O)[C@@H]1O

InChI Key: InChIKey=QPYJXFZUIJOGNX-UHFFFAOYSA-N

Data: 6 KI  23 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50182801   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
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Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen phosphorylase, liver form (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen debranching enzyme (Rabbit)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-galactosidase (Bovine)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
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Lysosomal acid glucosylceramidase (Bovine)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sucrase-isomaltase, intestinal (Rat)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sucrase-isomaltase, intestinal (Rat)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Lactase/phlorizin hydrolase (Rat)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20	n/a	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Rabbit)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen phosphorylase, liver form (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Rabbit)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen phosphorylase, liver form (Rat)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Non-lysosomal glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-galactosidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
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Beta-glucosidase (Agrobacterium tumefaciens)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Rabbit)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Trehalose synthase/amylase TreS (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-mannosidase (Bacteroides thetaiotaomicron )	BDBM50182801 (CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...) Show SMILES Show InChI	GoogleScholar	UniChem		9.00E+6	-2.90	n/a	n/a	n/a	n/a	n/a	5.6	37
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