BDBM50182939 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S)-2-(4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propan-1-one::CHEMBL377069

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCCC[C@H]1c1nc(c[nH]1)-c1ccccc1

InChI Key InChIKey=KLOMLLAPAMKOJE-GMAHTHKFSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50182939   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182939((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182939((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50182939((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50182939((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182939((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataEC50:  2nMAssay Description:Activity against mu opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182939((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataEC50:  37nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50182939((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataEC50:  2nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50182939((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataEC50:  37nMAssay Description:Agonist activity at delta opioid receptor expressed in CHO-hg cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed