BDBM50183448 CHEMBL3823478::US11773085, Compound B2

SMILES: CN1C=C(c2ccncc2C1=O)c3cc(c(c(c3)OC)CN(C)C)OC

InChI Key: InChIKey=RBUYFHLQNPJMQM-UHFFFAOYSA-N

Data: 2 KI  20 IC50  12 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 51 hits for monomerid = 50183448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2C8 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bromodomain-containing protein 7 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bromodomain-containing protein 2 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Activin receptor type-1 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Activin receptor type-2B (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Mouse)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	275	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 2C19 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 3A4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 2D6 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.316	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.794	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [133-239] (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Transcription initiation factor TFIID subunit 1-like (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
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Bromodomain adjacent to zinc finger domain protein 2B (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
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ATPase family AAA domain-containing protein 2B (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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CREB-binding protein (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
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Peregrin (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
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Nucleosome-remodeling factor subunit BPTF (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair