BDBM50183449 CHEMBL3823101::US11773085, Compound B23

SMILES: CN1C=C(c2ccncc2C1=O)c3cc(c(cc3OC)CN(C)C)OC

InChI Key: InChIKey=BJFSUDWKXGMUKA-UHFFFAOYSA-N

Data: 16 IC50  13 Kd

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50183449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2C8 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 9 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 7 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	239	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 7 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 7 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 4 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 4 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 4 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Chromatin remodeling regulator CECR2 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
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Chromatin remodeling regulator CECR2 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 9 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [133-239] (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
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Activin receptor type-2B (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Activin receptor type-1 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 2 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	418	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair