BDBM50183475 5-(3-Amino-propylamino)-7,10-dihydroxy-2-[2-(2-hydroxy-ethylamino)-ethyl]-2H-dibenzo[cd,g]indazol-6-one::CHEMBL203666::Piroxantrone hydrochloride

SMILES NCCCNc1ccc2n(CCNCCO)nc3-c4c(O)ccc(O)c4C(=O)c1c23

InChI Key InChIKey=QEWPVAOWLNMLRI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50183475   

TargetIntegrase(Human immunodeficiency virus 1)
University Of Houston

Curated by ChEMBL
LigandPNGBDBM50183475(5-(3-Amino-propylamino)-7,10-dihydroxy-2-[2-(2-hyd...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of 3'-processing activity of HIV1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
University Of Manitoba

Curated by ChEMBL
LigandPNGBDBM50183475(5-(3-Amino-propylamino)-7,10-dihydroxy-2-[2-(2-hyd...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human topoisomerase 2alpha decantation activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Houston

Curated by ChEMBL
LigandPNGBDBM50183475(5-(3-Amino-propylamino)-7,10-dihydroxy-2-[2-(2-hyd...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of strand transfer activity of HIV1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed