BDBM50183529 5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine::CHEMBL203054

SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc3ccccc3o1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=VGGMXMHOGPXDTQ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50183529   

TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50183529(5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50183529(5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50183529(5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50183529(5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl...)
Affinity DataIC50:  250nMAssay Description:Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed