BDBM50183559 CHEMBL374325::Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMeNle-D-Trp-Boc

SMILES CCCC[C@H](N(C)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NN[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@H](Cc1cn(C(=O)OC(C)(C)C)c2ccccc12)C(O)=O

InChI Key InChIKey=CHVZZDMXXHMJNM-BPYPMLAUSA-N

Data  5 KI  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50183559   

TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [125I]CCK8 from human CCK2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataIC50:  42nMAssay Description:Agonist activity at delta opioid receptor by inhibition of muscle contraction in electrically stimulated isolated mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataEC50:  0.650nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataEC50:  0.650nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to rat mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataEC50:  25nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataIC50:  2nMAssay Description:Agonist activity at mu opioid receptor by inhibition of muscle contraction in electrically stimulated isolated guinea pig ileum at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50183559(CHEMBL374325 | Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMe...)
Affinity DataIC50:  1.55E+3nMAssay Description:Displacement of [125I]CCK8 from human CCK2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed