BDBM50183678 4-(2-chlorobenzyl)phthalazin-1(2H)-one::CHEMBL378274

SMILES Clc1ccccc1Cc1n[nH]c(=O)c2ccccc12

InChI Key InChIKey=NXXMGRASOYMKFM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50183678   

TargetAlpha-1D adrenergic receptor(Rattus norvegicus (Rat))
Universidad De Salamanca

Curated by ChEMBL
LigandPNGBDBM50183678(4-(2-chlorobenzyl)phthalazin-1(2H)-one | CHEMBL378...)
Affinity DataEC50:  1.90E+3nMAssay Description:Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50183678(4-(2-chlorobenzyl)phthalazin-1(2H)-one | CHEMBL378...)
Affinity DataIC50:  8.54E+4nMAssay Description:Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50183678(4-(2-chlorobenzyl)phthalazin-1(2H)-one | CHEMBL378...)
Affinity DataIC50:  1.26E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed