BDBM50184143 1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-2,3-dihydro-1H-indole-5-carboxylic acid ((S)-2-morpholin-4-yl-2-oxo-1-phenyl-ethyl)-amide::CHEMBL437318

SMILES: FC(F)(F)c1ccc(cc1)-c1ccccc1C(=O)N1CCc2cc(ccc12)C(=O)N[C@H](C(=O)N1CCOCC1)c1ccccc1

InChI Key: InChIKey=JITLFKUHJGMLLE-HKBQPEDESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein (Homo sapiens (Human))	BDBM50184143 (1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-2,3-dih...) Show SMILES FC(F)(F)c1ccc(cc1)-c1ccccc1C(=O)N1CCc2cc(ccc12)C(=O)N[C@H](C(=O)N1CCOCC1)c1ccccc1 Show InChI InChI=1S/C35H30F3N3O4/c36-35(37,38)27-13-10-23(11-14-27)28-8-4-5-9-29(28)33(43)41-17-16-25-22-26(12-15-30(25)41)32(42)39-31(24-6-2-1-3-7-24)34(44)40-18-20-45-21-19-40/h1-15,22,31H,16-21H2,(H,39,42)/t31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibition of MTP in canine liver microsomes				Bioorg Med Chem Lett 16: 3039-42 (2006) Article DOI: 10.1016/j.bmcl.2006.02.058 BindingDB Entry DOI: 10.7270/Q2D21X68
					More data for this Ligand-Target Pair