BDBM50184587 (2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole::CHEMBL210484

SMILES C[C@@H]1C[C@H]2CNC[C@H]2N1c1nccc(n1)C(F)(F)F

InChI Key InChIKey=BHZWUADTFGRRTH-HRDYMLBCSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184587   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184587((2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  25nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184587((2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  57nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184587((2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  48nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed