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BDBM50184636 2,4,6-trioxo-6-(pyridin-2-yl)hexanoic acid::CHEMBL210962

SMILES: OC(=O)C(=O)CC(=O)CC(=O)c1ccccn1

InChI Key: InChIKey=BYCBWIGGSIQBFE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184636   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50184636
PNG
(2,4,6-trioxo-6-(pyridin-2-yl)hexanoic acid | CHEMB...)
Show SMILES OC(=O)C(=O)CC(=O)CC(=O)c1ccccn1
Show InChI InChI=1S/C11H9NO5/c13-7(6-10(15)11(16)17)5-9(14)8-3-1-2-4-12-8/h1-4H,5-6H2,(H,16,17)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of HIV1 recombinant integrase


Bioorg Med Chem Lett 16: 2920-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.010
BindingDB Entry DOI: 10.7270/Q2BV7HDK
More data for this
Ligand-Target Pair