BDBM50184774 CHEMBL3799221
SMILES CCOC(Cn1nc(-c2cnc3[nH]ccc3c2)c2c(N)ncnc12)OCC
InChI Key InChIKey=PABMYTICQCKZAG-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50184774
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 328nMAssay Description:Inhibition of human mTOR using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 566nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human KIT using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 598nMAssay Description:Inhibition of human RET using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair