BDBM50185306 CHEMBL3823873

SMILES COc1cccc(c1)-c1nc2ccccc2c(=S)[nH]1

InChI Key InChIKey=SGSOUQOVKICATR-UHFFFAOYSA-N

Data  3 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50185306   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185306(CHEMBL3823873)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant human CYP2C9 by P450-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185306(CHEMBL3823873)
Affinity DataEC50:  6.12E+3nMAssay Description:Agonist activity at human CAR3 expressed in African green monkey COS-1 cells cotransfected with RXRalpha after 24 hrs by CYP2B6-luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185306(CHEMBL3823873)
Affinity DataEC50:  510nMAssay Description:Agonist activity at VDR expressed in human HuH7 cells after 24 hrs by pDR3-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185306(CHEMBL3823873)
Affinity DataIC50:  750nMAssay Description:Inhibition of recombinant human CYP1A2 by P450-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185306(CHEMBL3823873)
Affinity DataEC50:  860nMAssay Description:Agonist activity at PXR expressed in human HepG2 cells after 24 hrs by p3A4-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185306(CHEMBL3823873)
Affinity DataEC50:  690nMAssay Description:Agonist activity at CAR LBD (108 to 348 residues) expressed in human HepG2 cells assessed as receptor binding to PGC1alpha by lanthascreenTR-FRET coa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185306(CHEMBL3823873)
Affinity DataIC50:  3.57E+4nMAssay Description:Inhibition of recombinant human CYP2B6 by P450-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185306(CHEMBL3823873)
Affinity DataEC50:  630nMAssay Description:Agonist activity at AHR expressed in human HepG2 cells after 24 hrs by pXRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed