BDBM50185368 CHEMBL2371910::CHEMBL439884::Pim[-Trp-Arg-Nva-Arg-Tyr-NH2]2

SMILES CCC[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=LTYROZHCAWVGIV-CTAKNGSMSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50185368   

TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185368(CHEMBL2371910 | CHEMBL439884 | Pim[-Trp-Arg-Nva-Ar...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [125I]hPP from human NPY4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185368(CHEMBL2371910 | CHEMBL439884 | Pim[-Trp-Arg-Nva-Ar...)
Affinity DataKi:  4.30nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185368(CHEMBL2371910 | CHEMBL439884 | Pim[-Trp-Arg-Nva-Ar...)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]NPY from human NPY1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185368(CHEMBL2371910 | CHEMBL439884 | Pim[-Trp-Arg-Nva-Ar...)
Affinity DataKi:  140nMAssay Description:Inhibitory activity against Opioid receptor kappa 1 expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185368(CHEMBL2371910 | CHEMBL439884 | Pim[-Trp-Arg-Nva-Ar...)
Affinity DataKi:  260nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185368(CHEMBL2371910 | CHEMBL439884 | Pim[-Trp-Arg-Nva-Ar...)
Affinity DataKi:  260nMAssay Description:Displacement of [125I]NPY from human NPY2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185368(CHEMBL2371910 | CHEMBL439884 | Pim[-Trp-Arg-Nva-Ar...)
Affinity DataEC50:  200nMAssay Description:Inhibitory activity against Opioid receptor kappa 1 expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185368(CHEMBL2371910 | CHEMBL439884 | Pim[-Trp-Arg-Nva-Ar...)
Affinity DataEC50:  220nMAssay Description:Inhibition of [3H]-FPP incorporation into biotin-linked K-ras decapeptide (CVLL) by bovine geranygeranyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed