BDBM50185409 (+/-)-(4aS,6R,8aS)-6-(4-chloro-benzenesulfonyl)-6-(2,5-difluoro-phenyl)-3-propyl-octahydro-benzo[1,2,6]thiadiazine 2,2-dioxide::CHEMBL377367

SMILES CCCN1C[C@@H]2C[C@](CC[C@@H]2NS1(=O)=O)(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=OBEHBYVZGXFFMR-UZQPLGKSSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185409   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Neuroscience Research Centre

Curated by ChEMBL

LigandBDBM50185409((+/-)-(4aS,6R,8aS)-6-(4-chloro-benzenesulfonyl)-6-...)Copy SMILESCopy InChI

Affinity DataIC50:  1.17nMAssay Description:Inhibition of gamma secretaseMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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