BDBM50185446 (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one::CHEMBL378104::cardamomin::cardamonin

SMILES COc1cc(O)cc(O)c1C(=O)\C=C\c1ccccc1

InChI Key InChIKey=NYSZJNUIVUBQMM-BQYQJAHWSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185446   

TargetGenome polyprotein(Dengue virus 2)
Sunway University College

Curated by ChEMBL
LigandPNGBDBM50185446((E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop...)
Affinity DataKi:  3.77E+5nMAssay Description:Inhibition of dengue2 virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50185446((E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human voltage-gated potassium channel Kv1.3 expressed in L929 cells by whole-cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-diphosphohydrolase 1(Schistosoma mansoni)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50185446((E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop...)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of Schistosoma mansoni ATPDase1 preincubated for 30 mins followed by addition of ATP/ADP by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM50185446((E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop...)
Affinity DataIC50:  1.14E+5nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50185446((E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop...)
Affinity DataIC50:  740nMAssay Description:Inhibition of human voltage-gated potassium channel Kv1.3 expressed in CGE22 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed