BDBM50185452 3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)-1H-pyrazol-3-yl)butanoic acid::CHEMBL209983

SMILES OC(=O)CC(Cc1cc(OCCc2ccc3CCCNc3n2)n[nH]1)c1ccc2OCOc2c1

InChI Key InChIKey=CTHYLBXDQVAGEJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185452   

TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185452(3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of alphavbeta5 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185452(3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  674nMAssay Description:Inhibition of alphavbeta6 integrin in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185452(3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  81.9nMAssay Description:Inhibition of alpha2bbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185452(3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185452(3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed