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BDBM50186129 2-{4-[(R)-3-(4-chloro-phenyl)-2-(2-2,3-dihydro-1H-indol-2-yl-acetylamino)-propionyl]-piperazin-1-yl}-2-cyclohexyl-N,N-diethyl-acetamide::CHEMBL209558

SMILES: CCN(CC)C(=O)C(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1Cc2ccccc2N1

InChI Key: InChIKey=SKYATFNOQJVJQZ-GMHFAUKKSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186129   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50186129
PNG
(2-{4-[(R)-3-(4-chloro-phenyl)-2-(2-2,3-dihydro-1H-...)
Show SMILES CCN(CC)C(=O)C(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1Cc2ccccc2N1
Show InChI InChI=1S/C35H48ClN5O3/c1-3-39(4-2)35(44)33(26-10-6-5-7-11-26)40-18-20-41(21-19-40)34(43)31(22-25-14-16-28(36)17-15-25)38-32(42)24-29-23-27-12-8-9-13-30(27)37-29/h8-9,12-17,26,29,31,33,37H,3-7,10-11,18-24H2,1-2H3,(H,38,42)/t29?,31-,33?/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
148n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells


Bioorg Med Chem Lett 16: 3449-53 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.002
BindingDB Entry DOI: 10.7270/Q2ST7PFS
More data for this
Ligand-Target Pair