BDBM50186426 CHEMBL210858::US10336721, ISO-1::US10968198, ISO-1::US8618147, ISO-1::methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate

SMILES: COC(=O)C[C@H]1CC(=NO1)c2ccc(cc2)O

InChI Key: InChIKey=AIXMJTYHQHQJLU-UHFFFAOYSA-N

Data: 5 KI  10 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50186426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Mouse)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	7.2	25
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Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage migration inhibitory factor (Rattus norvegicus)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		4.35E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50186426 (CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair