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BDBM50186673 (+/-)-3-difluoromethyl-1,2,3,4-tetrahydroisoquinoline::CHEMBL380310

SMILES: FC(F)C1Cc2ccccc2CN1

InChI Key: InChIKey=NWNOYQGTPGCCSQ-UHFFFAOYNA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186673   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phenylethanolamine N-methyltransferase


(Homo sapiens (Human))
BDBM50186673
PNG
((+/-)-3-difluoromethyl-1,2,3,4-tetrahydroisoquinol...)
Show SMILES FC(F)C1Cc2ccccc2CN1
Show InChI InChI=1/C10H11F2N/c11-10(12)9-5-7-3-1-2-4-8(7)6-13-9/h1-4,9-10,13H,5-6H2
PDB
MMDB

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Similars

Article
PubMed
3.40E+3n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Binding affinity to human PNMT


J Med Chem 49: 2939-52 (2006)


Article DOI: 10.1021/jm051262k
BindingDB Entry DOI: 10.7270/Q2K64HQ3
More data for this
Ligand-Target Pair