BDBM50186775 4-[[(6-chloro-5-fluoro-1H-benzoimidazol-2-ylmethyl)-amino]-(3'-cyano-biphenyl-4-yl)-methyl]-piperidine-1-carboxylic acid benzyl ester::CHEMBL211311

SMILES Fc1cc2[nH]c(CNC(C3CCN(CC3)C(=O)OCc3ccccc3)c3ccc(cc3)-c3cccc(c3)C#N)nc2cc1Cl

InChI Key InChIKey=JFMIBDAAZFALFW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186775   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186775(4-[[(6-chloro-5-fluoro-1H-benzoimidazol-2-ylmethyl...)
Affinity DataKi:  48nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186775(4-[[(6-chloro-5-fluoro-1H-benzoimidazol-2-ylmethyl...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed