BDBM50187114 CHEMBL3823303

SMILES CCc1cc(Nc2ncc(F)c(n2)-c2cnc3cccnn23)cc(OCCN2CCC(O)CC2)c1

InChI Key InChIKey=VZWXALUQDOYOJQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50187114   

TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187114(CHEMBL3823303)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant FLAG-tagged TAK1 kinase domain (unknown origin) expressed in baculovirus expression system coexpressing TAB using biotin-la...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50187114(CHEMBL3823303)
Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50187114(CHEMBL3823303)
Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187114(CHEMBL3823303)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant FLAG-tagged TAK1 (unknown origin) co-expressed with TAB (unknown origin) in baculovirus using BT-MKK as substrate after 1 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187114(CHEMBL3823303)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant FLAG-tagged TAK1 (unknown origin) co-expressed with TAB (unknown origin) in baculovirus using BT-MKK as substrate after 1 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed