BDBM50187115 CHEMBL3822835

SMILES Cc1cc(NC(=O)Nc2cc(nn2-c2cccc(c2)C#N)C(C)(C)C)ccc1Oc1ccncc1

InChI Key InChIKey=BVCVUQMOUMAXKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187115   

TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187115(CHEMBL3822835)
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant TAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187115(CHEMBL3822835)
Affinity DataIC50: 156nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187115(CHEMBL3822835)
Affinity DataIC50: 156nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed