BDBM50187627 CHEMBL445149::N-(1-phenyl-3-(3-methoxyphenyl)-1H-pyrazol-3-yl)benzamide

SMILES COc1cccc(c1)-c1cc(NC(=O)c2ccccc2)n(n1)-c1ccccc1

InChI Key InChIKey=AOYKTDCRRAIYDY-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187627   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187627(CHEMBL445149 | N-(1-phenyl-3-(3-methoxyphenyl)-1H-...)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187627(CHEMBL445149 | N-(1-phenyl-3-(3-methoxyphenyl)-1H-...)
Affinity DataEC50:  600nMAssay Description:Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed