BDBM50187657 3,6-dihydroxy-2-phenyl-4H-chromen-4-one::3,6-dihydroxy-flavone::3,6-dihydroxyflavone::CHEMBL210411

SMILES Oc1ccc2oc(-c3ccccc3)c(O)c(=O)c2c1

InChI Key InChIKey=XHLOLFKZCUCROE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50187657   

TargetDipeptidyl peptidase 3(Homo sapiens (Human))
Josip Juraj Strossmayer University Of Osijek

LigandPNGBDBM50187657(3,6-dihydroxy-2-phenyl-4H-chromen-4-one | 3,6-dihy...)
Affinity DataIC50:  5.64E+4nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of flavonoids toward human DPP III was assayed in a 50 mM Tris-HCl buffer, pH 7.4. In brief, recombinant human DPP III (0.29 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50187657(3,6-dihydroxy-2-phenyl-4H-chromen-4-one | 3,6-dihy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 15-hLO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
University Of Chemistry And Technology Prague

Curated by ChEMBL
LigandPNGBDBM50187657(3,6-dihydroxy-2-phenyl-4H-chromen-4-one | 3,6-dihy...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1a preincubated for 10 mins followed by addition of ATP and measured after 40 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50187657(3,6-dihydroxy-2-phenyl-4H-chromen-4-one | 3,6-dihy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50187657(3,6-dihydroxy-2-phenyl-4H-chromen-4-one | 3,6-dihy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed