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BDBM50188516 2-(2-amino-N-methylacetamido)acetic acid::CHEMBL175737::Gly-Sar::Gly-sarcosin::[(2-Amino-acetyl)-methyl-amino]-acetic acid::[(ammonioacetyl)(methyl)amino]acetate

SMILES: CN(CC(O)=O)C(=O)CN

InChI Key: InChIKey=VYAMLSCELQQRAE-UHFFFAOYSA-N

Data: 3 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188516   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 15 member 2


(Homo sapiens (Human))
BDBM50188516
PNG
(2-(2-amino-N-methylacetamido)acetic acid | CHEMBL1...)
Show SMILES CN(CC(O)=O)C(=O)CN
Show InChI InChI=1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)
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PubMed
6.40E+4n/an/an/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Cephalexin uptake in SKPT cells


J Biol Chem 270: 25672-7 (1995)


BindingDB Entry DOI: 10.7270/Q2H70JP8
More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens (Human))
BDBM50188516
PNG
(2-(2-amino-N-methylacetamido)acetic acid | CHEMBL1...)
Show SMILES CN(CC(O)=O)C(=O)CN
Show InChI InChI=1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)
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Article
PubMed
8.30E+5n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition constant (Ki) for human intestinal peptide carrier


J Med Chem 46: 5725-34 (2003)


Article DOI: 10.1021/jm030976x
BindingDB Entry DOI: 10.7270/Q22N531C
More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens (Human))
BDBM50188516
PNG
(2-(2-amino-N-methylacetamido)acetic acid | CHEMBL1...)
Show SMILES CN(CC(O)=O)C(=O)CN
Show InChI InChI=1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)
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PubMed
1.28E+7n/an/an/an/an/an/an/an/a



Rutgers University

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of VACV uptake in PEPT1-expressing CHO cells


J Pharmacol Exp Ther 289: 448-54 (1999)


BindingDB Entry DOI: 10.7270/Q2QJ7JKJ
More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens (Human))
BDBM50188516
PNG
(2-(2-amino-N-methylacetamido)acetic acid | CHEMBL1...)
Show SMILES CN(CC(O)=O)C(=O)CN
Show InChI InChI=1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)
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CHEMBL
PC cid
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Article
PubMed
n/an/an/an/a 5.40E+5n/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Activation of human PEPT1 expressed in MDCK cells


J Med Chem 49: 3636-44 (2006)


Article DOI: 10.1021/jm0511029
BindingDB Entry DOI: 10.7270/Q2P55P9R
More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens (Human))
BDBM50188516
PNG
(2-(2-amino-N-methylacetamido)acetic acid | CHEMBL1...)
Show SMILES CN(CC(O)=O)C(=O)CN
Show InChI InChI=1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)
Reactome pathway
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CHEMBL
PC cid
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Article
PubMed
n/an/a 1.16E+6n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells


J Med Chem 49: 3636-44 (2006)


Article DOI: 10.1021/jm0511029
BindingDB Entry DOI: 10.7270/Q2P55P9R
More data for this
Ligand-Target Pair