BDBM50188736 3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)urea::CHEMBL378895

SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1cc(CN3CCN(C)CC3)ccc-21)C(=O)Nc1cc(F)cc(c1)C(F)(F)F

InChI Key InChIKey=SLZDAHQKZCFNCA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50188736   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188736(3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188736(3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188736(3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of FLT1 at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188736(3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-...)
Affinity DataIC50: 233nMAssay Description:Inhibition of KDR phosphorylation in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed