BDBM50188814 8-[2-(4-fluoro-phenyl)-cyclohexyl]-4-phenyl-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL378616

SMILES Fc1ccc(cc1)C1CCCCC1N1CCC2(CC1)C(CNC2=O)c1ccccc1

InChI Key InChIKey=VIUIHCNTOLSYJT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188814   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188814(8-[2-(4-fluoro-phenyl)-cyclohexyl]-4-phenyl-2,8-di...)
Affinity DataEC50:  48nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed