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BDBM50189502 CHEMBL3827832

SMILES: CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1

InChI Key: InChIKey=PFSWASUQURIOOR-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189502   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 84


(Homo sapiens (Human))
BDBM50189502
PNG
(CHEMBL3827832)
Show SMILES CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H,2-8H2,1H3,(H3,13,14,15,16,17)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 438n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens (Human))
BDBM50189502
PNG
(CHEMBL3827832)
Show SMILES CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H,2-8H2,1H3,(H3,13,14,15,16,17)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 512n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at human GPR84 by [35S]GTPgammaS binding assay


J Med Chem 60: 3636-3655 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01593
BindingDB Entry DOI: 10.7270/Q289180W
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens (Human))
BDBM50189502
PNG
(CHEMBL3827832)
Show SMILES CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H,2-8H2,1H3,(H3,13,14,15,16,17)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 512n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at human GPR84 fused with bovine Galphai1 protein expressed in baculovirus infected sf9 cell membrane incubated for 1 hr by [35S]GTP...


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens (Human))
BDBM50189502
PNG
(CHEMBL3827832)
Show SMILES CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H,2-8H2,1H3,(H3,13,14,15,16,17)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 653n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair