BDBM50189771 5-[5-(2,4-difluorophenyl)furan-2-ylmethylene]thiazolidine-2,4-dione::CHEMBL378107

SMILES Fc1ccc(-c2ccc(\C=C3/SC(=O)NC3=O)o2)c(F)c1

InChI Key InChIKey=FWEPNYNOKOHTNJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189771   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
The University of Jordan

Curated by ChEMBL

LigandBDBM50189771(5-[5-(2,4-difluorophenyl)furan-2-ylmethylene]thiaz...)Copy SMILESCopy InChI

Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) assessed as decrease in fluorescence intensity using phosphorylated substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2016
Entry Details Article
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
The University of Jordan

Curated by ChEMBL

LigandBDBM50189771(5-[5-(2,4-difluorophenyl)furan-2-ylmethylene]thiaz...)Copy SMILESCopy InChI

Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL