BDBM50189778 CHEMBL211405::N-tert-butyl-5-amino-4-(3-methoxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide::ORG-41841::cid_9887381

SMILES COc1cccc(c1)-c1nc(SC)nc2sc(C(=O)NC(C)(C)C)c(N)c12

InChI Key InChIKey=DVSFSADBOJYPGF-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50189778   

TargetSentrin-specific protease 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50189778(CHEMBL211405 | N-tert-butyl-5-amino-4-(3-methoxyph...)
Affinity DataIC50:  1.52E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSentrin-specific protease 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50189778(CHEMBL211405 | N-tert-butyl-5-amino-4-(3-methoxyph...)
Affinity DataIC50:  1.91E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLutropin-choriogonadotropic hormone receptor(Homo sapiens (Human))
Nih Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM50189778(CHEMBL211405 | N-tert-butyl-5-amino-4-(3-methoxyph...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at LHCGR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin receptor(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50189778(CHEMBL211405 | N-tert-butyl-5-amino-4-(3-methoxyph...)
Affinity DataEC50:  6.50E+3nMAssay Description:Agonist activity at TSHR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C11(Rattus norvegicus)
Nih Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM50189778(CHEMBL211405 | N-tert-butyl-5-amino-4-(3-methoxyph...)
Affinity DataEC50:  7.70E+3nMAssay Description:Agonist activity at TSHR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLutropin-choriogonadotropic hormone receptor(Homo sapiens (Human))
Nih Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM50189778(CHEMBL211405 | N-tert-butyl-5-amino-4-(3-methoxyph...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed