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BDBM50189798 CHEMBL3827811

SMILES: CC(Oc1ccc2[nH]nc(-c3nc4ccccc4s3)c2c1)c1c(Cl)cncc1Cl

InChI Key: InChIKey=LRZVAVFNSMWGDR-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189798   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50189798
PNG
(CHEMBL3827811)
Show SMILES CC(Oc1ccc2[nH]nc(-c3nc4ccccc4s3)c2c1)c1c(Cl)cncc1Cl
Show InChI InChI=1/C21H14Cl2N4OS/c1-11(19-14(22)9-24-10-15(19)23)28-12-6-7-16-13(8-12)20(27-26-16)21-25-17-4-2-3-5-18(17)29-21/h2-11H,1H3,(H,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 228n/an/an/an/an/an/a



East China University of Science & Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human FGFR1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA


J Med Chem 59: 6690-708 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00056
BindingDB Entry DOI: 10.7270/Q2474CT3
More data for this
Ligand-Target Pair