BDBM50189992 CHEMBL385479::N-(3-chloro-2-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

SMILES COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OCCCN1CCOCC1

InChI Key InChIKey=BIFFYWVZRGCPLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189992   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50189992(CHEMBL385479 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human EGFR using poly[Glu:Tyr] (4:1) as substrate measured after 20 mins in presence of [gamma33P]ATP by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50189992(CHEMBL385479 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  18nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed