BDBM50190473 CHEMBL377688::N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(2-hydroxyethyl)guanidine

SMILES NC(NC(=O)c1nc(Cl)c(N)nc1N)=NCCO

InChI Key InChIKey=XDNGHABKLHZEOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190473   

TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190473(CHEMBL377688 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  107nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed