BDBM50190488 4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)guanidino]-butyl}benzoic acid methyl ester::CHEMBL379756

SMILES COC(=O)c1ccc(CCCCN=C(N)NC(=O)c2nc(Cl)c(N)nc2N)cc1

InChI Key InChIKey=BLDRVAKLJPKASG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190488   

TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190488(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50:  22nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed