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BDBM50190506 CHEMBL3828497

SMILES: CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)C[C@H](CO)NC1=O

InChI Key: InChIKey=OBRREKIEIBFZAE-ZZVCLBLWNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190506   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Disintegrin and metalloproteinase domain-containing protein 8


(Homo sapiens (Human))
BDBM50190506
PNG
(CHEMBL3828497)
Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)C[C@H](CO)NC1=O
Show InChI InChI=1/C32H59N11O9/c1-18(2)14-23-30(51)38-19(17-44)15-25(45)39-20(8-3-5-11-33)27(48)43-24(16-26(46)47)31(52)41-21(9-4-6-12-34)28(49)40-22(29(50)42-23)10-7-13-37-32(35)36/h18-24,44H,3-17,33-34H2,1-2H3,(H,38,51)(H,39,45)(H,40,49)(H,41,52)(H,42,50)(H,43,48)(H,46,47)(H4,35,36,37)/t19-,20+,21+,22+,23+,24+/s2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 157n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...


Bioorg Med Chem 24: 4032-4037 (2016)


Article DOI: 10.1016/j.bmc.2016.06.042
BindingDB Entry DOI: 10.7270/Q2ST7RS3
More data for this
Ligand-Target Pair