BDBM50190706 8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine::CHEMBL209230::N-benzyl-4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonamide

SMILES CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(=O)(=O)NCc1ccccc1

InChI Key InChIKey=MQFLPQUECNRXNT-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50190706   

TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50190706(8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]PSB298 from human recombinant adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50190706(8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine...)
Affinity DataKi:  4.20nMAssay Description:Antagonist activity against human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50190706(8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50190706(8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine...)
Affinity DataKi:  26.7nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50190706(8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine...)
Affinity DataKi:  54.8nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50190706(8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine...)
Affinity DataKi:  54.8nMAssay Description:Antagonist activity against human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50190706(8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine...)
Affinity DataKi:  162nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50190706(8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine...)
Affinity DataKi:  162nMAssay Description:Displacement of [3H]MSX2 from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50190706(8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity against human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed