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BDBM50191009 (S)-1-(4-(2-(1-amino-3-methylbutyl)-4-(trifluoromethyl)phenyl)piperazin-1-yl)-4-(4-chlorophenyl)butane-1,4-dione::CHEMBL380018

SMILES: CC(C)C[C@H](N)c1cc(ccc1N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1)C(F)(F)F

InChI Key: InChIKey=MBUOVFVHMFPNRZ-QFIPXVFZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191009   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50191009
PNG
((S)-1-(4-(2-(1-amino-3-methylbutyl)-4-(trifluorome...)
Show SMILES CC(C)C[C@H](N)c1cc(ccc1N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C26H31ClF3N3O2/c1-17(2)15-22(31)21-16-19(26(28,29)30)5-8-23(21)32-11-13-33(14-12-32)25(35)10-9-24(34)18-3-6-20(27)7-4-18/h3-8,16-17,22H,9-15,31H2,1-2H3/t22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
820n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cells


Bioorg Med Chem Lett 16: 4800-3 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.075
BindingDB Entry DOI: 10.7270/Q2NC60VS
More data for this
Ligand-Target Pair