BDBM50191342 3alpha-hydroxy-5alpha-pregnan-20-one::CHEMBL207538
SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI Key InChIKey=AURFZBICLPNKBZ-SYBPFIFISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50191342
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
CoCensys Inc
Curated by ChEMBL
CoCensys Inc
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 76nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
CoCensys Inc
Curated by ChEMBL
CoCensys Inc
Curated by ChEMBL
Affinity DataEC50: 237nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University of Manchester
Curated by ChEMBL
University of Manchester
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair