BindingDB logo
myBDB logout

BDBM50191454 1-(4-((4-(2,5-dimethyl-1-(thiophen-2-ylmethyl)-1H-pyrrole-3-carbonyl)morpholin-2-yl)methoxy)-2-fluorophenyl)ethanone::CHEMBL377268

SMILES: CC(=O)c1ccc(OCC2CN(CCO2)C(=O)c2cc(C)n(Cc3cccs3)c2C)cc1F

InChI Key: InChIKey=RXOGAVZZMFTDKW-UHFFFAOYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191454   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Rattus norvegicus (rat))
BDBM50191454
PNG
(1-(4-((4-(2,5-dimethyl-1-(thiophen-2-ylmethyl)-1H-...)
Show SMILES CC(=O)c1ccc(OCC2CN(CCO2)C(=O)c2cc(C)n(Cc3cccs3)c2C)cc1F
Show InChI InChI=1/C25H27FN2O4S/c1-16-11-23(17(2)28(16)14-21-5-4-10-33-21)25(30)27-8-9-31-20(13-27)15-32-19-6-7-22(18(3)29)24(26)12-19/h4-7,10-12,20H,8-9,13-15H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



University of Kuopio

Curated by ChEMBL


Assay Description
Inhibition of Wistar rat brain FAAH


J Med Chem 49: 4650-6 (2006)


Article DOI: 10.1021/jm060394q
BindingDB Entry DOI: 10.7270/Q2Q52P8G
More data for this
Ligand-Target Pair