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BDBM50191758 4'-fluoro-biphenyl-4-carboxylic acid (3-morpholin-4-ylmethyl-quinolin-8-ylmethyl)-amide::CHEMBL214547

SMILES: Fc1ccc(cc1)-c1ccc(cc1)C(=O)NCc1cccc2cc(CN3CCOCC3)cnc12

InChI Key: InChIKey=CYGWVWRDYSVELO-UHFFFAOYSA-N

Data: 1 KI  1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191758   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50191758
PNG
(4'-fluoro-biphenyl-4-carboxylic acid (3-morpholin-...)
Show SMILES Fc1ccc(cc1)-c1ccc(cc1)C(=O)NCc1cccc2cc(CN3CCOCC3)cnc12
Show InChI InChI=1S/C28H26FN3O2/c29-26-10-8-22(9-11-26)21-4-6-23(7-5-21)28(33)31-18-25-3-1-2-24-16-20(17-30-27(24)25)19-32-12-14-34-15-13-32/h1-11,16-17H,12-15,18-19H2,(H,31,33)
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UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.41E+3n/an/an/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity to MCHR1 by radioligand binding assay


Bioorg Med Chem Lett 16: 5207-11 (2006)


Article DOI: 10.1016/j.bmcl.2006.07.006
BindingDB Entry DOI: 10.7270/Q2SX6CV3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50191758
PNG
(4'-fluoro-biphenyl-4-carboxylic acid (3-morpholin-...)
Show SMILES Fc1ccc(cc1)-c1ccc(cc1)C(=O)NCc1cccc2cc(CN3CCOCC3)cnc12
Show InChI InChI=1S/C28H26FN3O2/c29-26-10-8-22(9-11-26)21-4-6-23(7-5-21)28(33)31-18-25-3-1-2-24-16-20(17-30-27(24)25)19-32-12-14-34-15-13-32/h1-11,16-17H,12-15,18-19H2,(H,31,33)
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UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.47E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from 5HT2C receptor


Bioorg Med Chem Lett 16: 5207-11 (2006)


Article DOI: 10.1016/j.bmcl.2006.07.006
BindingDB Entry DOI: 10.7270/Q2SX6CV3
More data for this
Ligand-Target Pair