BDBM50191866 1-adamantan-1-yl-3-piperidin-4-ylmethyl-urea::CHEMBL216287::US10383835, Compound II::US11123311, Compound II

SMILES O=C(NCC1CCNCC1)NC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=ZQMNKAGVCNSSIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191866   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50191866(1-adamantan-1-yl-3-piperidin-4-ylmethyl-urea | CHE...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50191866(1-adamantan-1-yl-3-piperidin-4-ylmethyl-urea | CHE...)
Affinity DataIC50:  4.20E+3nMAssay Description:Any of a number of standard assays for determining epoxide hydrolase activity can be used to determine inhibition of sEH. For example, suitable assay...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpoxide hydrolase 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50191866(1-adamantan-1-yl-3-piperidin-4-ylmethyl-urea | CHE...)
Affinity DataIC50:  4.20E+3nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent