BDBM50191961 4-cyano-5-ethyl-1-methyl-3-(2'-methylsulfanyl-biphenyl-4-yl)-1H-pyrrole-2-carboxylic acid::CHEMBL215090

SMILES CCc1c(C#N)c(c(C(O)=O)n1C)-c1ccc(cc1)-c1ccccc1SC

InChI Key InChIKey=BFVMMSQKTYYTMS-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50191961   

TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191961(4-cyano-5-ethyl-1-methyl-3-(2'-methylsulfanyl-biph...)
Affinity DataEC50:  77nMAssay Description:Activity at human recombinant iGluR4 flop expressed in HEK293 cells measured as change in intracellular calcium ion concentration in presence of glut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191961(4-cyano-5-ethyl-1-methyl-3-(2'-methylsulfanyl-biph...)
Affinity DataEC50:  57nMAssay Description:Activity at human recombinant iGluR2 flip expressed in HEK293 cells measured as change in intracellular calcium ion concentration in presence of glut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191961(4-cyano-5-ethyl-1-methyl-3-(2'-methylsulfanyl-biph...)
Affinity DataEC50:  105nMAssay Description:Activity at human recombinant iGluR4 flip expressed in HEK293 cells measured as change in intracellular calcium ion concentration in presence of glut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191961(4-cyano-5-ethyl-1-methyl-3-(2'-methylsulfanyl-biph...)
Affinity DataEC50:  32nMAssay Description:Activity at human recombinant iGluR2 flop expressed in HEK293 cells measured as change in intracellular calcium ion concentration in presence of glut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed