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BDBM50192205 2-chloro-N-(4-(5-(cyclobutanecarboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)benzamide::CHEMBL214445

SMILES: Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CCC3)cc2[nH]1

InChI Key: InChIKey=UGUHVOJNAPXDDU-UHFFFAOYSA-N

Data: 2 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192205   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
photoreceptor-specific nuclear receptor


(Homo sapiens (Human))
BDBM50192205
PNG
(2-chloro-N-(4-(5-(cyclobutanecarboxamido)-1H-benzo...)
Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CCC3)cc2[nH]1
Show InChI InChI=1S/C25H21ClN4O2/c26-20-7-2-1-6-19(20)25(32)27-17-10-8-15(9-11-17)23-29-21-13-12-18(14-22(21)30-23)28-24(31)16-4-3-5-16/h1-2,6-14,16H,3-5H2,(H,27,32)(H,28,31)(H,29,30)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 986n/an/an/an/a



Merck & Co.

Curated by ChEMBL


Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells


Bioorg Med Chem Lett 16: 5001-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D
More data for this
Ligand-Target Pair
photoreceptor-specific nuclear receptor


(Homo sapiens (Human))
BDBM50192205
PNG
(2-chloro-N-(4-(5-(cyclobutanecarboxamido)-1H-benzo...)
Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CCC3)cc2[nH]1
Show InChI InChI=1S/C25H21ClN4O2/c26-20-7-2-1-6-19(20)25(32)27-17-10-8-15(9-11-17)23-29-21-13-12-18(14-22(21)30-23)28-24(31)16-4-3-5-16/h1-2,6-14,16H,3-5H2,(H,27,32)(H,28,31)(H,29,30)
PDB

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UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.33E+3n/an/an/an/a



Merck & Co.

Curated by ChEMBL


Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay


Bioorg Med Chem Lett 16: 5001-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D
More data for this
Ligand-Target Pair